Measurement of small, dense lipoproteins. Usefulness of the Tg/HDL index compared to direct LDL measurement
نویسندگان
چکیده
Abstract Funding Acknowledgements Type of funding sources: None. Main source(s): Ninguna Introduction The Triglyceride/HDL (Tg/HDL) ratio when > 2 is translated into the presence small, dense lipoproteins (sdLDL), which are more atherogenic and help us measure global lipid risk regardless LDL levels. There possibility measuring sdLDL directly, but it not performed in routine clinical practice. objective our study was to analyze correlation TG/HDL index with direct measurement cardiovascular (CVR). Materials methods Patients who were treated cardiology from July 1 – September 30, 2022 analyzed consecutively determination profile requested. This considered sdLDL> 50 mg/dl. Results n 75. Mean age 60 ± 15 years. 37.3% women. 49.3% hypertensive, 48% dyslipidemic, 22.7% diabetic, 32% smokers, 58.7% very high CVR 54.7% lipid-lowering treatment. levels 84.3±37 mg/dl, non-HDL 110±39 triglycerides 139±75 remnant cholesterol 27.8 ±15 LDL-sd 34±20 mg/dl Tg/HDL 3.5±±2. Tg/HDL>2 had mean 36± 23 vs 29.7 14 (p0.06) those Tg/HDL>3 39.8± 26 28.9± 12 ±(p<0.02). All patients LDL> mg/dL Tg/HDL>2, however 60% LDL<50 (p0.01), only 37% (p<0.001). (Table 1. Relationship between profile, Tg/HDl LDL-SD) 20% high/high RCV LDL>50 9.1% moderate 12.5% low RCV. Conclusions may be useful identifying primarily 3.
منابع مشابه
Direct Measurement of LDL Cholesterol
able amounts of radiolabeled dextran in the plasma protein fraction [15]. Consequently, we do not think this mechanism plays a substantial role in producing the lower than expected dextran concentrations seen in the present study. The dextran we used had a mean molecular mass of 70 000 Da. Thus, some quantity of lower-molecular-mass dextran could have leaked out of the vascular space and distri...
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ژورنال
عنوان ژورنال: European Journal of Preventive Cardiology
سال: 2023
ISSN: ['2047-4881', '2047-4873']
DOI: https://doi.org/10.1093/eurjpc/zwad125.110